PowerISO (64-bit) is a powerful and widely used software for managing disk image files, including ISO, BIN, NRG, CDI, and more. Developed by Power Software Ltd., it allows users to create, edit, extract, convert, compress, encrypt, and mount virtual disc images. It also supports burning images to CDs, DVDs, and Blu-ray discs, making it a go-to tool for system administrators, developers, and general users who frequently handle optical media.
However, some users may decide to uninstall PowerISO (64-bit) due to performance issues, switching to alternative tools like Daemon Tools or WinCDEmu, or simply because they no longer need the software. Given that PowerISO installs virtual drivers and integrates deeply with the Windows file system, standard uninstallation methods may not fully remove all related components.
This guide provides several methods to completely remove PowerISO (64-bit) from your system. We will highlight important distinctions between 32-bit and 64-bit systems, as well as differences between Windows 10 and Windows 11. Each method includes detailed step-by-step instructions, key points, precautions, success rate estimates, and an analysis of its drawbacks. The final method introduces Perfect Uninstaller, a third-party utility designed for deep and comprehensive software removal. In the conclusion, we provide a professional perspective to help you make an informed decision about which uninstallation method suits your needs best.
Method 1: Uninstall via Settings App (Windows 10 / Windows 11)
Steps:
- Open Settings
- Press
Win + Ito open the Settings app.
- Go to Apps > Installed Apps
- In Windows 10, navigate to Apps > Apps & features.
- In Windows 11, go directly to Installed apps under the Apps section.
- Search for PowerISO
- Use the search bar at the top and type “PowerISO”.
- Uninstall the Application
- Click on PowerISO (x64) or PowerISO and then click Uninstall.
- Confirm when prompted and wait for the process to complete.
Notes:
- This method works only if PowerISO was installed as a modern application or via an installer that registers in the system.
- On 64-bit systems, ensure you are removing the correct x64 version.
- Some older installers may not appear here.
Success Rate:
- ~75–80% successful removal of the main program files.
Drawbacks:
- Does not remove residual configuration files, cached logs, or registry entries unless manually deleted.
- Cannot uninstall deeply embedded services such as virtual drive drivers.
- May leave behind startup items or background processes if not fully terminated.
Method 2: Using Control Panel (Legacy Interface)
The Control Panel remains a reliable option for managing installed applications, especially for advanced users or those who prefer a more traditional interface.
Steps:
- Open Control Panel
- Type “Control Panel” in the Start menu and open it.
- Navigate to Programs > Uninstall a Program
- Locate PowerISO (x64)
- Scroll through the list and select PowerISO (x64) or PowerISO.
- Uninstall the Application
- Click Uninstall and follow the prompts to complete the process.
Notes:
- Compatible with both 32-bit and 64-bit systems, but on 64-bit machines, ensure you’re uninstalling the correct x64 version.
- Works on both Windows 10 and Windows 11, though the layout may differ slightly.
Success Rate:
- ~77–82% successful removal of the main program files.
Drawbacks:
- May not fully clean up user profiles, shared system folders, or plugin directories.
- Less intuitive than the modern Settings interface.
- Still leaves behind some configuration and cache files.
Method 3: Manual File and Registry Cleanup (Post-Uninstall)
After uninstalling via any of the above methods, you can perform manual cleanup to remove any remaining files or registry entries left behind by PowerISO (64-bit).
Steps:
- Delete App Data Folders
- Navigate to:
C:\Program Files\PowerISO C:\Users\YourUsername\AppData\Roaming\PowerISO C:\Users\YourUsername\AppData\Local\PowerISO
- Clear Temp Files
- Delete:
C:\Users\YourUsername\AppData\Local\Temp\PowerISO*
- Clean Registry Entries
- Open Registry Editor (
regedit) as admin. - Navigate to:
HKEY_CURRENT_USER\Software\PowerISO HKEY_LOCAL_MACHINE\SOFTWARE\PowerISO
For 64-bit systems, also check:HKEY_LOCAL_MACHINE\SOFTWARE\Wow6432Node\PowerISO - Delete these keys if they exist.
- ⚠️ Warning: Always back up the registry before making changes.
Notes:
- This method requires technical expertise.
- Works on both 32-bit and 64-bit systems.
- Especially useful for advanced users or system administrators.
Success Rate:
- ~92–96% complete removal if executed properly.
Drawbacks:
- Time-consuming and error-prone.
- Risk of accidental file or registry deletion.
- Not recommended for novice users.
Method 4: Using Perfect Uninstaller (Third-Party Tool)
Perfect Uninstaller is a powerful utility designed to perform deep and comprehensive software removal, including leftover files, registry entries, and cached data that standard uninstallers often miss.
Step-by-Step Instructions:
Step 1: Download Perfect Uninstaller
- Visit the official website of Perfect Uninstaller (ensure it’s a trusted source).
- Download the correct version based on your system:
- 32-bit systems: Install 32-bit version.
- 64-bit systems: Install 64-bit version for full compatibility.
Step 2: Install and Launch the Software
- Run the installer and follow the setup instructions.
- Launch the application after installation.
Step 3: Locate PowerISO (64-bit)
- In the main interface, scroll through the list of installed programs.
- Find “PowerISO (x64)” or “PowerISO” and click on it.
Step 4: Initiate Uninstallation
- Click the Uninstall button.
- The tool will begin removing PowerISO, displaying real-time progress.
- During uninstallation, it will remove:
- Application files
- Registry entries
- Startup items
- Virtual drive drivers (if applicable)
- User-specific data
Step 5: Perform Deep Cleanup
- After uninstalling, use the Scan for Leftovers feature.
- Let the tool scan for any remaining files or registry fragments.
- Select all found items and click Delete to ensure a clean system.
Notes:
- Perfect Uninstaller offers automated and comprehensive removal.
- Works seamlessly on both Windows 10 and Windows 11.
- Ideal for users who want to avoid manual file hunting and registry editing.
Success Rate:
- ~98–100% complete removal, depending on software version and database updates.
Drawbacks:
- Requires downloading third-party software, which may raise security concerns.
- Some versions may include bundled software or ads.
- Paid versions often offer better support and functionality.
Conclusion
PowerISO (64-bit) is a robust disk imaging and virtualization tool that integrates deeply with system components such as virtual drive drivers and registry settings. As a result, standard uninstallation methods may not be sufficient to fully remove it from your system.
From a professional standpoint, while native tools like the Settings app and Control Panel are suitable for basic uninstallations, they often fail to deliver a thorough cleanup. These methods typically succeed in removing the core application but fall short in eliminating hidden configurations and temporary files — especially those tied to external devices or system-level components.
For a truly effective and hassle-free experience, Perfect Uninstaller stands out as the most reliable choice. With a success rate of up to 98–100%, it ensures that PowerISO (64-bit) and all its remnants are removed permanently from your system.
However, always exercise caution when downloading third-party software — verify the source and consider opting for a paid or premium version for enhanced safety and support.
In summary, while built-in Windows tools provide partial solutions, Perfect Uninstaller remains the superior option for achieving a clean, optimized, and secure system after uninstalling PowerISO (64-bit).